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Biomedical Informatics & Engineering Research Laboratory (BIRL)
Research Overview

Research

BIRL integrates biological and clinical data to model complex disease and support translational decision systems. Our portfolio spans cancer systems biology, plant systems biology, proteomics, public health epidemiology, and neuroscience, with active work on multiscale modeling software, antiviral discovery, and e-health monitoring.

5
Overarching Themes
3
Computational Approaches
4
Translational Areas
1
Integrated Research Vision

Core Research Areas

The core of our research program comprises computational disease modeling, omics analytics, public-health intelligence, and translational biomedical software development.

Integrated Research Pipeline

Each stage in our workflow connects computational development to biological interpretation and real-world use in medicine and public health.

01

Problem Framing

Clinical and biological questions are translated into formal, testable system hypotheses.

02

Model and Algorithm Design

Mechanistic and data-driven models are developed for multiscale disease interpretation.

03

Platform Engineering

Reproducible software pipelines are implemented for omics analysis and simulation workflows.

04

Translational Impact

Outputs are mapped to precision therapeutics, public-health analytics, and decision support.

Computational Core

  • Systems modeling: ODE, Boolean, rules-based, and cellular-automaton frameworks.
  • Proteomics intelligence: top-down and bottom-up analysis, ranking, and quantitation pipelines.
  • Software architecture: interoperable biomedical tooling across modern and legacy data stacks.
  • Scientific engines: platform-grade implementations supporting robust experimental analytics.

Expected Outcomes

The integrated pipeline converts computation into evidence, and evidence into deployable biomedical value for oncology, proteomics, antivirals, and healthcare systems.

Validated Models Software Platforms Clinical Insights Policy-ready Analytics

Thematic Portfolio Snapshot

Systems and Therapeutic Modeling

Cancer systems biology, multiscale simulation, and precision strategy design.

Omics and Molecular Analytics

Proteomics engines, metabolomics profiling, and high-performance sequence interpretation.

Population and Clinical Informatics

Public-health epidemiology, risk modeling, and intelligent healthcare decision support.

Experimental-Computational Integration

Plant systems biology and neuroscience methods connected to translational software pipelines.

Representative Contributions

A curated innovation mural linking flagship tools with measurable translational impact.

ELECANS ATLANTIS SPECTRUM PERCEPTRON HCV Modeling Epidemiology Analytics

These platforms represent the continuum from computational method design to deployable biomedical and population-health intelligence.

Thesis Supervision

Thesis supervision records of PhD, MS, and BS Students.

PhD Thesis Supervision

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MS Thesis Supervision

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BS Thesis Supervision

No. Topic of Research Scholar(s) Award Year
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